Search Results - apoptosis
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Apoptosis inducing compounds
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Small Molecule
Compounds
Apoptosis - Cancer - Therapeutics
Background
Adamantyl-substituted
retinoid related molecules are a unique class of compounds which have been
found to induce apoptosis, or cell death, in many different tumor types....
Published: April 07, 2010
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Inventor(s): Marcia Dawson
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Small Molecule Compounds
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3-CL-AHPN, an apoptosis inducer
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Small Molecule Compounds
Apoptosis - Cancer - Therapeutics
The current invention provides compounds or retinoid and non
retinoid analogues (3-cl-AHPN) to induce apoptosis in cancer
cells.
Features
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Induces apoptosis in
the M07e h...
Published: October 09, 2009
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Inventor(s): Marcia Dawson, Xiao-kun Zhang
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Small Molecule Compounds
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Homing Peptides
Most
therapeutic treatments, whether radio- or chemo- therapies to treat cancer,
drugs to treat cardiovascular disease or antibiotics to treat wounds are
delivered systemically, causing
undesired and even toxic
events in healthy organ systems. Multiple licensing opportunities are available
in the field of homing peptides, which confer selec...
Published: August 20, 2009
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Inventor(s):
Keywords(s): Apoptosis, Cancer
Category(s): Bundled Technologies
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Apoptosis modulators
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Assays
Apoptosis - Cancer - Therapeutics
A small molecule screening method for proapoptotic Bcl-2
converters.
Features
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Converts Bcl-B from
anti-apoptotic to a pro-apoptotic
Background
Programmed cell death...
Published: August 17, 2009
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Inventor(s): Eduard Sergienko, Ph.D., Kenneth Yip, John Reed, M.D., Ph.D.
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Assays
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Retinoid X receptor modulators
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Small Molecule
Compounds
Apoptosis - Cancer - Therapeutics
Compounds that
modulate retinoid X receptor transport from the nucleus to the cytoplasm
of a cell, to induce apoptosis for the treatment of cancer and autoimmune
disorders.
Lead
In...
Published: August 14, 2009
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Inventor(s): Xiao-kun Zhang
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Small Molecule Compounds
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Bcl-2 conversion peptides
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Peptides
Apoptosis - Cancer- Therapeutics
The Sanford-Burnham
Medical Research Institute is seeking a company interested in
commercializing a novel method of inducing cell death in cancerous cells.
Researchers at Sanford-Burnham have discovered p...
Published: August 14, 2009
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Inventor(s): Arnold Satterthwait, Ph.D.
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Peptides
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BID, a BCL-2 family member, inhibitors
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Small Molecule
Compounds Apoptosis - Cancer- Immunology and
Inflammation - Therapeutics
Compounds that inhibit BID a BCL-2 family member for the treatment
of cell death disorders.
Features
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Caspase activity can be modulated
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Published: August 12, 2009
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Inventor(s): John Reed
Keywords(s): Apoptosis, Cancer, Immunology & Inflammation, Therapeutics
Category(s): Small Molecule Compounds
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Chimeric peptides to induce apoptosis
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Peptides
Apoptosis - Cancer - Therapeutics
A melanoma specific apoptosis inducing chimeric peptide for the
inhibition of Caspase-9 to treat cancer.
Lead
Inventor
Guy Salvesen, Ph.D.
Salvesen lab
homepage
S...
Published: August 12, 2009
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Inventor(s): Guy Salvesen
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Peptides
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CD40 associated proteins
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Peptides
Apoptosis - Immunology
Peptides of
CD40 associated proteins (CAP) for the treatment or diagnosis of diseases
characterized by aberrant CD40 expression, such as X linked
immunodeficiency syndrome.
Lead
Inventor ...
Published: August 12, 2009
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Inventor(s): John Reed
Keywords(s): Apoptosis, Immunology
Category(s): Peptides
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Tumor-penetrating peptides
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Peptides
Apoptosis - Cancer - Therapeutics
Tissue selective homing peptides containing CENDR and iRDG elements
to enhance internalization and penetration of compounds, for the treatment
of cancer.
Features
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Published: July 23, 2009
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Inventor(s): Erkki Ruoslahti
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Peptides
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