Search Results - cancer
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Apoptosis inducing compounds
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Small Molecule
Compounds
Apoptosis - Cancer - Therapeutics
Background
Adamantyl-substituted
retinoid related molecules are a unique class of compounds which have been
found to induce apoptosis, or cell death, in many different tumor types....
Published: April 07, 2010
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Inventor(s): Marcia Dawson
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Small Molecule Compounds
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EphB Receptor-binding Peptides
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Peptides
Cancer - Therapeutics
Peptides that bind EphB receptors, disrupting receptor-ligand
interactions, to modulate the activity of EphB receptors and stimulate
apoptosis.
Background
The Eph receptors are a large family of r...
Published: February 12, 2010
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Inventor(s): Elena Pasquale
Keywords(s): Cancer, Therapeutics
Category(s): Peptides
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Tumor targeting peptides
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Peptides
Cancer - Therapeutics
Tumor targeting peptides that can bind to cellular carbohydrate
sequences.
Background
A major obstacle in treating cancer is the relative lack
of agents that can selectively target the cancer while...
Published: February 12, 2010
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Inventor(s): Michiko Fukuda
Keywords(s): Cancer, Therapeutics
Category(s): Peptides
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Modulators of Kaposis sarcoma-associated herpes virus latency
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Biologics
Cancer - Therapeutics
BackgroundKaposi’s
sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8,
is associated not only with B-lymphoproliferative diseases such as primary
effusion lymphoma, but also with Kaposi’s...
Published: December 14, 2009
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Inventor(s): Tariq Rana, Ph.D.
Keywords(s): Cancer, Therapeutics
Category(s): Biologicals
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Targeting of albumin-embedded taxol nanoparticles to tumors
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Nanoparticle
Cancer - Therapeutics
Background
Nanomedicine is an emerging field that uses nanoparticles to
facilitate the diagnosis and treatment of diseases. Nanoparticles are attractive
because multiple functions can be built into them, su...
Published: October 29, 2009
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Inventor(s): Erkki Ruoslahti
Keywords(s): Cancer, Therapeutics
Category(s): Nanoparticle
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3-CL-AHPN, an apoptosis inducer
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Small Molecule Compounds
Apoptosis - Cancer - Therapeutics
The current invention provides compounds or retinoid and non
retinoid analogues (3-cl-AHPN) to induce apoptosis in cancer
cells.
Features
·
Induces apoptosis in
the M07e h...
Published: October 09, 2009
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Inventor(s): Marcia Dawson, Xiao-kun Zhang
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Small Molecule Compounds
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Cell migration inhibitors
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Peptides
Cancer - Therapeutics
Synthetic peptides to inhibit cell migration or
invasion.
Lead Inventor
Erkki
Ruoslahti, M.D., Ph.D.
Ruoslahti lab homepage
Selected References
List of references...
Published: October 09, 2009
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Inventor(s): Erkki Ruoslahti
Keywords(s): Cancer, Therapeutics
Category(s): Peptides
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Cell adhesion modulators
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Biologics
Cancer - Therapeutics
The current invention
provides soluble and membrane-bound forms of human
.beta.-1,6-N-acetylglucosaminyltransferase,an I-branching enzyme (IGnT)
implicated in the regulation
of glycosyltransferases for cel...
Published: October 09, 2009
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Inventor(s): Minoru Fukuda, Ph.D.
Keywords(s): Cancer, Therapeutics
Category(s): Biologicals
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E-selectin cell adhesion modulators
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Biologics
Cancer - Therapeutics
E-selectin mediated cell adhesion antagonists for controlling
inflammation and metastasis.
Lead Inventor
Michiko Fukuda, Ph.D.
Fukuda lab homepage
Selected References
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Published: October 09, 2009
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Inventor(s): Michiko Fukuda, Ph.D.
Keywords(s): Cancer, Therapeutics
Category(s): Biologicals
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EGFR expression in microsatellite instability colon cancers
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Biologics
Biomarker - Cancer - Therapeutics
Uses of EGFr as a diagnostic and prognostic biomarker in
microsatellite instability positive gastroinestinal
tumors.
Features
Improves
the specificity of colon cancer treatments
Ba...
Published: October 01, 2009
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Inventor(s): Manuel Perucho, Ph.D.
Keywords(s): Biomarker, Cancer, Therapeutics
Category(s): Biologicals
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