Search Results - signal transduction
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Proapoptotic peptides
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Peptides
Apoptosis - Signal Transduction -
Therapeutics
Peptides of
proapoptotic dependence domains for the modulation of apoptosis.
Lead
InventorDale Bredesen, M.D.
Selected ReferencesJ Mol Neurosci. 2000
Dec;15(3):215-29. Rabizadeh,
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Published: June 23, 2009
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Inventor(s): Dale Bredesen, M.D.
Keywords(s): Apoptosis, Signal Transduction, Therapeutics
Category(s): Peptides
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Identification and sequencing of transciption factor gene targets
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Assays
Signal Transduction
A method to identify, amplify and sequence genes that are
being regulated by transcription factors.
Lead Investigator
Eileen Adamson, Ph.D.
Patent Information
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Published: June 10, 2009
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Inventor(s): Eileen Adamson, Ph.D.
Keywords(s): Signal Transduction
Category(s): Assays
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Neural cell differentiation from stem cells
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Stem Cell Biology
Neurobiology - Signal Transduction
The Sanford-Burnham Medical Research
Institute is seeking a company interested in commercializing a
method of differentiating nervous system cells from embryonic stem cells,
by modulating the MEF2C pathway, for the treatment ...
Published: May 22, 2009
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Inventor(s): Stuart Lipton
Keywords(s): Neurobiology, Signal Transduction
Category(s): Stem Cell Biology
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Modulating apoptosis through the PAAD domain
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Peptides
Apoptosis - Cancer - Diagnostics - Signal
Transduction - Therapeutics
The Sanford-Burnham Medical Research
Institute is seeking a company interested in commercializing novel
polypeptides that contain and bind PAAD death domains to modulate
apoptosis.
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Published: May 22, 2009
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Inventor(s): John Reed
Keywords(s): Apoptosis, Cancer, Diagnostics, Signal Transduction, Therapeutics
Category(s): Peptides
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Necrosis modulators
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Assays
Apoptosis - Diagnostics - Immunology and
Inflammation - Signal Transduction - Therapeutics
The Sanford-Burnham Medical Research
Institute is seeking a company interested in commercializing novel
methods to identify paraptosis regulators as an alternative to
apopto...
Published: May 22, 2009
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Inventor(s): Dale Bredesen, M.D.
Keywords(s): Apoptosis, Diagnostics, Immunology & Inflammation, Signal Transduction, Therapeutics
Category(s): Assays
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Prostate cancer diagnostic methods and treatments
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Assays
Apoptosis - Cancer - Diagnostics - Post
Translational Modifications - Signal Transduction -
Therapeutics
The
Sanford-Burnham Medical Research Institute is seeking a company interested
in commercializing a novel method of screening
prostate epithelial cel...
Published: May 22, 2009
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Inventor(s): Jeffrey Smith, Ph.D.
Keywords(s): Apoptosis, Cancer, Diagnostics, Post Translational Modifications, Signal Transduction, Therapeutics
Category(s): Assays
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Inhibitors of Eph receptor-ligand binding
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Peptides
Apoptosis - Signal Transduction -
Therapeutics
Peptides that bind Eph receptors, disrupting receptor-ligand
interactions, to modulate the activity of Eph receptors and stimulate
apoptosis.
Background
The
Eph receptors are...
Published: May 22, 2009
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Inventor(s): Elena Pasquale
Keywords(s): Apoptosis, Signal Transduction, Therapeutics
Category(s): Peptides
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Modulating the cell attachment regulated apoptosis pathway
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Biologics
Apoptosis - Cancer - Signal Transduction -
Therapeutics
Compounds
that regulate cell attachment apoptosis (anoikis) through the Bit1/AES
pathway.Lead
Inventor Erkki
Ruoslahti, M.D., Ph.D.Ruoslahti lab
homepageSelected
ReferencesList of referen...
Published: May 22, 2009
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Inventor(s): Erkki Ruoslahti, M.D., Ph.D.
Keywords(s): Apoptosis, Cancer, Signal Transduction, Therapeutics
Category(s): Biologicals
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Prevention and treatment of neurodegenerative disorders
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Biologics
Therapeutics - Signal Transduction -
Neurobiology
A method of inducing a
synergistic neuroprotective effect through the erythropoietin and insulin
like growth factor pathways.
Lead Inventor
Stuart Lipton, M.D., Ph.D.
Lipton l...
Published: May 22, 2009
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Inventor(s): Stuart Lipton, M.D., Ph.D.
Keywords(s): Signal Transduction, Therapeutics, Neurobiology
Category(s): Biologicals
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Inhibitors of the Shp2 pathway for stem cell culture
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Small Molecule
Compounds
Assays - Signal Transduction - Stem Cell
Biology
The Sanford-Burnham Medical Research
Institute is seeking a company interested in commercializing novel
inhibitors of the Shp2 pathway to modulate stem cell self renewal,
differentiation, sur...
Published: May 22, 2009
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Inventor(s): Gen-Sheng Feng
Keywords(s): Signal Transduction, Stem Cell Biology, Assays
Category(s): Small Molecule Compounds
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