Search Results - therapeutics
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Methods to treat symptoms of aging
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Biologicals
Aging - Diabetes - Metabolic Diseases
- Stem Cell Biology -
Therapeutics
The current invention provides methods of modulating
the insulin/IGF pathway to treat symptoms related to aging.
Features
ยท
Reduces symptoms of
aging
Ba...
Published: June 03, 2010
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Inventor(s): Sean Oldham, Ph.D.
Keywords(s): Aging, Biomarker, Diabetes, Metabolic Diseases, Stem Cell Biology, Therapeutics
Category(s): Biologicals
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Allosteric inhibitors of mGluR2
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Small Molecule
Compounds Neurobiology - Therapeutics
The Sanford-Burnham Medical Research Institute is seeking a partner
to commercialize novel positive allosteric modulators of mGluR2 for the
treatment of neurological diseases and disorders.
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Published: May 19, 2010
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Inventor(s): Nicholas Cosford
Keywords(s): Neurobiology, Therapeutics
Category(s): Small Molecule Compounds
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CD44 modulation in helper T cell survival and memory
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Biologics
Diabetes - Immunology - Infectious
Diseases - Therapeutics
Features
The
Sanford-Burnham Medical Research Institute is seeking a partner to
commercialize methods of modulating the CD44 pathway to treat immune and
autoimmune disorders.
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Published: May 17, 2010
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Inventor(s): Linda Bradley, Ph.D.
Keywords(s): Immunology, Infectious Diseases, Therapeutics, Diabetes
Category(s): Biologicals
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Pulmonary and fibrotic disorder homing peptides
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Peptides
Diagnostics - Therapeutics
Lead
Inventor
Erkki Ruoslahti, M.D.,
Ph.D.
Ruoslahti lab
homepage
Selected References
List of references via
Pubmed
Patent
Information ...
Published: May 03, 2010
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Inventor(s): Erkki Ruoslahti
Keywords(s): Diagnostics, Therapeutics
Category(s): Peptides
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Apoptosis inducing compounds
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Small Molecule
Compounds
Apoptosis - Cancer - Therapeutics
Background
Adamantyl-substituted
retinoid related molecules are a unique class of compounds which have been
found to induce apoptosis, or cell death, in many different tumor types....
Published: April 07, 2010
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Inventor(s): Marcia Dawson
Keywords(s): Apoptosis, Cancer, Therapeutics
Category(s): Small Molecule Compounds
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EphB Receptor-binding Peptides
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Peptides
Cancer - Therapeutics
Peptides that bind EphB receptors, disrupting receptor-ligand
interactions, to modulate the activity of EphB receptors and stimulate
apoptosis.
Background
The Eph receptors are a large family of r...
Published: February 12, 2010
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Inventor(s): Elena Pasquale
Keywords(s): Cancer, Therapeutics
Category(s): Peptides
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Tumor targeting peptides
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Peptides
Cancer - Therapeutics
Tumor targeting peptides that can bind to cellular carbohydrate
sequences.
Background
A major obstacle in treating cancer is the relative lack
of agents that can selectively target the cancer while...
Published: February 12, 2010
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Inventor(s): Michiko Fukuda
Keywords(s): Cancer, Therapeutics
Category(s): Peptides
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Eph A2/4 inhibitors
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Small Molecule
Compounds
Neurobiology - Therapeutics
Background
The Eph receptors are best known for their role in the developing
and injured nervous system and in the developing cardiovascular system,
but have recently been implicated in...
Published: December 15, 2009
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Inventor(s): Elena Pasquale
Keywords(s): Neurobiology, Therapeutics
Category(s): Small Molecule Compounds
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Cardiotoxic drug screening assay
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Assays
Cardiovascular Disease - Therapeutics
Cardiac arrhythmia and sudden cardiac death are major
pharmaceutical targets from therapeutic and toxicologic standpoints.
Recently, several cardiac drugs have been withdrawn from the market or
restrictively labeled due to toxic...
Published: December 15, 2009
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Inventor(s): Mark Mercola, Ph.D.
Keywords(s): Cardiovascular Disease, Therapeutics
Category(s): Assays
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Antibodies to West Nile virus infection
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Biologics
Infectious Diseases - Therapeutics
West
Nile virus (WNV) is transmitted to humans from mosquito bites and can have
varied effects ranging from asymptomatic infections to a neuroinvasive
form called West Nile meningitis, which can be de...
Published: December 15, 2009
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Inventor(s): Alex Strongin, Ph.D.
Keywords(s): Infectious Diseases, Therapeutics
Category(s): Biologicals
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